WHAT IS Zoletil™?
Zoletil™ comprises a synergistic balance between Tiletamine & Zolazepam. Tiletamine – a dissociative anesthetic. Zolazepam – a benzodiazepine tranquilizer group of drugs.
RECOMMENDED FOR
– As a sedative (for restraint, diagnostic or painless examination procedures)
– As a sole anesthetic for minor surgeries or in combination with a potent analgesic for major surgeries
– As an induction agent, prior to inhalant anesthesia
WHY CHOOSE ZOLETIL™?
With two proven ingredients, Zoletil™ is a smart option for general anesthesia combining sedation, muscle relaxation, and analgesia in dogs and cats.
Zoletil™ offers peace of mind owing to its rapid onset of action, the smooth recovery process, and wide safety margin. With the use of Zoletil™ comes the convenience of flexible dosing based on the procedure to be conducted, multiple modes of administration – IV or IM, and the possibility to integrate Zoletil™ into existing anesthetic protocols.
In addition to the 30 years of experience with Zoletil™ in small animal practice, Zoletil™ has versatility and scientific recognition in a plethora of wildlife species.
COMPOSITION
Zoletil™ 50 = One vial of 675 mg freeze-dried powder contains:
Tiletamine (as Hydrochloride) 125 mg
Zolazepam (as Hydrochloride) 125 mg
Excipients qs
ONE VIAL OF 5 ML SOLVENT CONTAINS:
Sterile Water for injections lP 5 ml
ONE ML OF RECONSTITUTED SOLUTION CONTAINS:
Tiletamine (as Hydrochloride) 25 mg
Zolazepam (as Hydrochloride) 25 mg
Zoletil™ 100 = One vial of 970 mg freeze-dried powder contains:
Tiletamine (as Hydrochloride) 250 mg
Zolazepam (as Hydrochloride) 250 mg
Excipients qs
ONE VIAL OF 5 ML SOLVENT CONTAINS:
Sterile Water for injections lP 5 ml
ONE ML OF RECONSTITUTED SOLUTION CONTAINS:
Tiletamine (as Hydrochloride) 50 mg
Zolazepam (as Hydrochloride) 50 mg
DOSAGE & DIRECTIONS FOR USE
| In Dogs | Intramuscular route | Intravenous route |
| Tests and procedures causing little pain | 7 to 10 mg/kg BW | 5 mg/kg BW |
| Minor surgical procedures, anaesthesia of short duration | 10 to 15 mg/kg BW | 7.5 mg/kg BW |
| Painful intervention, major surgical procedures | 15 to 25 mg/kg BW | 10 mg/kg BW |
| In Cats | Intramuscular route | Intravenous route |
| Tests and procedures causing little pain | 10 mg/kg BW | 5 mg/kg BW |
| Surgeries | 15 mg/kg BW | 7.5 mg/kg BW |
Multiple administrations to be avoided and is associated with delayed recovery, but if given, re-administration should only be at 1/3 to ½ of the initial dose, but the total dosage is should not exceed 26.4 mg/kg.
STORAGE
Prior to opening store in a cool & dry place, protect from exposure to light. Post-re-constitution store at 2 to 8°C and use within 24 hours.
SUGGESTIONS
- 12 hours of fasting prior to anaesthesia
- Removal of anti-parasite collars 24 hours prior to anaesthesia
- Anticholinergic drugs (such as Atropine) may be used 15 mins. prior to Zoletil™ administration
- Apneustic breathing may be observed in cats given in IV mode. This abnormality may last for up to 15 mins & then breathing returns to normal. If not, respiratory assistance needs to be provided.
- Eyes remain open and hence should be protected from excessive dryness (especially in major surgeries, a damp cloth can be placed upon the eyes)
- Animal to be placed in a calm environment during the recovery phase
CONTRAINDICATIONS
- Cardiac disease or severe hypertension; respiratory disease; renal, pancreatic, and hepatic insufficiency; head trauma or intracranial tumors
- Caesarean section or in pregnant bitches and queens
- In conjunction with phenothiazine tranquilizers
Reviews
Clear filtersThere are no reviews yet.